Trial – Apomorphine (P03)

To whom is this relevant?

Those with Parkinson’s disease who have a good response to Levodopa therapy, are taking it at least three times a day AND experience “Off” periods.

What is being trialled and where?

Research at Derriford Hospital in Plymouth is investigating oral Apomorphine. This is a new chemical formulation developed by Sunovion which is taken by placing a thin film under the tongue.

The aim of this research is to see how movement may be improved by taking oral Apomorphine,  and compare this with the existing method of injected Apomorphine. 25 people are needed for this Trial.

What is involved?

The first visit to the Trials Unit at Derriford will assess your suitability to take part. A range of assessments will be performed and you will have the opportunity to ask questions. If you are suitable for the Trial you will be invited to give your consent. You will be required to take both oral Apomorphine and subcutaneous Apomorphine injection during the course of the study.

More information is given in the Participant Information Sheet and the Study Drug Flow Chart.

Interested in taking part?

Please contact Dr Camille Carroll’s research team on 01752 432048 or email

Further Information

The international Drug Trial Protocol reference is CTH-302